Affiliate Marketing Secrets

I recently wrote a how-to book that has a niche market – but quite a large niche market – that is untapped. I grew up in Minnesota and am currently living in Iowa, and am looking for someone willing to take this project on – but with the resources I’ve looked at I am having trouble finding a literary agent that will take on my book. I appreciate any help anybody can offer me! I am not sure if I am being naive in thinking it will help, but I feel having a “midwest connection” with a literary agent and/or publisher could/would help my cause. Thanks!